Proteins · one protein

Insulin

UniProt P01308 · 110 residues

AlphaFold's confidence, residue by residue: 0 very high (90 and above) · 14 confident (70 to 90) · 40 low (50 to 70) · 56 very low (below 50).

Ask this protein

• What does it look like? 110 residues: 0% very high confidence, 51% very low.
• Where could a drug bind?
• Can I print it and fill it in by hand?
• Can you bet its confidence bar?

The next questions its numbers invite

• Is that floppy bit broken or working? 56 of its 110 residues are below pLDDT 50.
• Where should it be drawn sketchy? 56 of its 110 residues are below pLDDT 50.
• What does a single-chain model leave out? Every AlphaFold DB entry is one chain on its own: no partners, metals or cofactors.

These follow-ups come from a short hand-written table that reads only the numbers above: many residues below 50 invites the disorder games; most at 90 or above invites the one about movement. They are questions to try, not findings about this protein.

AlphaFold DB model v6 for UniProt P01308, from Fold Commons' snapshot of 2026-10-04. A prediction, not an experiment.