Model: AlphaFold DB · CC BY 4.0 · prediction, not experiment.
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A tumour-suppressor protein that helps a cell pause to repair its DNA — or self-destruct when the damage is too great. Its gene is mutated in a large fraction of human cancers, which is why it is one of the most-studied proteins in biology.
Every AlphaFold model is coloured by pLDDT, the model's own per-residue confidence —
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