Fold Commons

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CRISPR Cas9

Cas9 is a scissors protein that bacteria use against viruses. Scientists turned it into a tool to edit DNA on purpose.

CRISPR Cas9: its AlphaFold model, drawn in one colour
Picture, in one colour: AlphaFold DB model v6 for UniProt Q99ZW2, from Fold Commons' snapshot of 2026-10-22. A prediction, not an experiment.

See it in 3D

Fun fact

The first CRISPR medicine was approved in 2023 for sickle cell.

Words to know

NGSS alignment

Structure

Rendered in FoldLens Junior from AlphaFold Database entry Q99ZW2. See the underlying prediction at alphafold.ebi.ac.uk/entry/Q99ZW2.

For teachers and platforms

This page is the canonical share URL for the FoldLens Junior CRISPR Cas9 entry. Educational platforms can embed it via the standard OEmbed protocol — the discovery link is in the page head, the JSON body is at /junior/oembed/cas9.json, and the query endpoint at /junior/oembed?url=…&format=json redirects to the same body.