Proteins · one protein

ABL1 kinase

UniProt P00519 · 1130 residues

AlphaFold's confidence, residue by residue: 417 very high (90 and above) · 106 confident (70 to 90) · 51 low (50 to 70) · 556 very low (below 50).

Ask this protein

• What does it look like? 1130 residues: 37% very high confidence, 49% very low.
• Where could a drug bind?
• Can I print it and fill it in by hand?

The next questions its numbers invite

• Is that floppy bit broken or working? 556 of its 1130 residues are below pLDDT 50.
• Where should it be drawn sketchy? 556 of its 1130 residues are below pLDDT 50.
• Could it be more than one piece, and how sure are they of each other? It is 1130 residues long; long chains are often built from domains.
• What does a single-chain model leave out? Every AlphaFold DB entry is one chain on its own: no partners, metals or cofactors.

These follow-ups come from a short hand-written table that reads only the numbers above: many residues below 50 invites the disorder games; most at 90 or above invites the one about movement. They are questions to try, not findings about this protein.

AlphaFold DB model v6 for UniProt P00519, from Fold Commons' snapshot of 2026-10-04. A prediction, not an experiment.